Cannabis is a plant genus in the Cannabaceae family with psychoactive properties, known as Cannabis sativa, Cannabis indica, and Cannabis ruderalis.
Three species recognized in science classifications: Cannabis sativa, Cannabis indica, Cannabis ruderalis
What is the “DIFFERENCE” BETWEEN HEMP & CANNABIS
- Hemp and marijuana are simply broad classifications of Cannabis.
- Not different “species” or “strains.”
- Legally, “Hemp” is a term used to classify varieties of Cannabis that contain 0.3% or less THC content (by dry weight).
- Agriculture Improvement Act of 2018, or the 2018 Farm Bill.
CANNALAWS IN THE US TODAY
- Cannabis is still classified as a Schedule 1 controlled substance along with heroin.
- Schedule 1 substances have:
- no currently accepted medical use in U.S.
- a lack of accepted safety for use under medical supervision, and
- a high potential for abuse.
- Cocaine and Meth are listed as Schedule 2 Substances, those that have some medical value.
THE ENDOCANNABINOID SYSTEM (ECS)
- The ECS is made up of CB1 and CB2 receptors found throughout the body, including in the brain and other organs, connective tissues, glands, and immune cells.
- These receptors respond to the body’s own endocannabinoids, but also respond to phytocannabinoids, or cannabinoids from the cannabis plant.
- CBD & THC are the most commonly known cannabinoids.
- Different types:
- Synthetic cannabinoids
- Kind of like essential oils, terpenes are what that give the plant different aromas, flavors, and perhaps therapeutic effects.
- Terpenes are not unique to cannabis, in fact they’re found in a lot of other herbs, fruits, and plants!
- Flavonoids are made up of groups of polyphenolic compounds that act as secondary metabolites to a myriad of plants and fungi.
- They account for roughly 10% of the known compounds in cannabis with around 20 known varieties.
The Entourage Effect is the “whole” of cannabis compounds (cannabinoids, terpenes, and flavonoids) working synergistically as they are created in the plant.
CANNABIS AFFECTS EACH PERSON DIFFERENTLY
- Current mood, expectations, and atmosphere all play an important role.
- You need to consider, Are other drugs being consumed?
- Alcohol, illegal
drugs, over-the-counter medications,
- How much Experience does the user have? What is their tolerance level like?
- Does the individual have Mental health conditions
- What Strain is being consumed
- What is the Potency or strength of the cannabis
- What is the Method of consumption? Inhalation, Topical, Edible?
Can someone “Overdose” on THC ?
- The British Journal of Psychiatry reported that cannabis is “safe in overdose;” in other words, it’s physically impossible for a human to die as a direct result of a cannabis overdose.
- This is due to the therapeutic index of cannabis.
What is the THERAPUTIC INDEX?
The margin of safety between how much of a drug or substance a person needs to feel the desired effects of that drug, and how much of a drug or substance will result in death.
Mean lethal dose (LD50) the minimum amount of a substance that would result in a fatality in 50% of the population
Mean Effective Dose (ED50) the minimum amount of a substance that allows 50% of the population to achieve the desired effects